Publications
For all publications, please see the PubMed listing
Skeletal Health and Orthopedic REsearch (SHORE) Program
What is SHORE?
The Skeletal Health and Orthopedic REsearch (SHORE) Program at Hospital for Special Surgery was founded in 2024 with the mission of advancing the understanding of and treatment for orthopedic disorders and other diseases of the skeleton. This focus extends the long history of HSS as the first orthopedics specialty hospital and as a center for orthopedic research, including key research on scoliosis by John Cobb in the 1940s, opening one of the first dedicated orthopedic research facilities in 1960, and performing the first modern artificial knee replacement in 1974. To accomplish this mission, the center integrates basic and translational scientists with surgeon and clinician scientists alongside core facilities specialized for musculoskeletal research.
SHORE scientists have made important contributions to identify the stem cells that form the skeleton, how orthopedic implants integrate with the surrounding skeleton, mechanisms of spine deformities, and new pathways leading to bone destruction in arthritis and osteoporosis. Work by our scientists has helped elucidate key features of bone quality that predict surgical success and complication risk in orthopedic surgery patients.
Directors
Matthew B. Greenblatt, MD, PhD
Emily Margaret Stein, MD, MS
Faculty
Ugur Ayturk, PhD
Mathias P. Bostrom, MD
Alberto Carli, MD
Matthew E. Cunningham, MD, PhD
Sravisht Iyer, MD
Kyle W. Morse, MD
Kyung Hyun Park-Min, PhD
Cathleen L. Raggio, MD
Xu Yang, MD, PhD
Baohong Zhao, PhD
SHORE Cores
- High-resolution peripheral QCT Core
(Director Emily Stein, 212.606.1970, steine@hss.edu) - Molecular Histopathology Core Laboratory
(Director Miguel Otero, 212.774.7561, oterom@hss.edu) - Micro-CT Core
(Director Kyung-Hyun Park-Min, 212.774.7631, parkmink@hss.edu)
Recent Accomplishments
- Congratulations to Xu Yang and colleagues on their publication “Prevention and treatment of peri-implant fibrosis by functionally inhibiting skeletal cells expressing the leptin receptor” in Nature Biomedical Engineering.
- Congratulations to Baohong Zhao and colleagues on their publication “Long non-coding RNA Malat1 fine-tunes bone homeostasis and repair by orchestrating cellular crosstalk and β-catenin-OPG/Jagged1 pathway” in eLife.
- Congratulations to Kyung-Hyun Park-Min and colleagues on their publication “Cellular signatures in human blood track bone mineral density in postmenopausal women" published in JCI Insight.
- Congratulations to Ezgi Aydin receiving the inaugural Francis Glorieux Research Fellowship from the Canadian Osteogenesis Imperfect Society!
SHORE in the News
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